WebJan 29, 2014 · 3β-Hydroxysteroid-Δ24 reductase (DHCR24) is an endoplasmic reticulum (ER)-localized multifunctional enzyme that possesses anti-apoptotic and cholesterol-synthesizing activities. Accumulating evidence suggests that ER stress is involved in the pathogenesis of neurodegenerative disease. In this study, we investigated whether … WebSep 23, 2024 · Mainly through the recent work of Glass and coworkers (8, 9), we identified Δ 24-dehydrocholesterol reductase (DHCR24; also called Seladin-1) as a promising target for controlling lipid metabolism, possibly allowing its reprogramming.DHCR24 is the terminal enzyme in cholesterol biosynthesis, catalyzing the transformation of desmosterol to …
Serum DHCR24 Auto-antibody as a new Biomarker for Progression …
WebSamples were blocked with blocking buffer (1.5 hr, 22°C), incubated with DHCR24 polyclonal antibody (Product # PA5-100181) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit. Western blot analysis of DHCR24 in K562 cell lysate (left lane: treated with blocking peptide). Samples were incubated with DHCR24 ... WebWhat buffer format is "DHCR24 Antibody - N-terminal region : HRP (ARP47072_P050-HRP)" provided in? This item is provided in "Liquid. Purified antibody is supplied in high … great clips martinsburg west virginia
DHCR24: A Novel HCC Biomarker at a Glance
WebDHCR24 Antibody (PA5-92446) in WB. Western Blot analysis of DHCR24 in extracts of various cell lines using DHCR24 Polyclonal Antibody ( Product # PA5-92446) at a dilution of 1:1000. A HRP Goat Anti-Rabbit IgG (H+L) secondary antibody was used at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. WebDHCR24 is a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol … WebApr 19, 2024 · Background: 24-dehydrocholesterol reductase (Dhcr24) catalyzes the last step of cholesterol biosynthesis, which is required for normal development and anti … great clips menomonie wi