Metabolism of vinyl chloride
Web9 feb. 2024 · It is well known that the risk for developing chronic liver injury is influenced by multiple factors, such as genetics, comorbidities, and/or lifestyle choices, such as diet. … Web13 mrt. 2024 · Metabolism occurs through CYP2E1 to form epoxide intermediates which are subsequently detoxified via glutathione conjugation and renally excreted. [17] Animal studies suggest that while metabolites get widely distributed throughout the body, they do not accumulate in the tissue, even with chronic exposure.
Metabolism of vinyl chloride
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Web1 mrt. 2024 · Vinyl chloride is primarily metabolized to chloroethylene oxide by hepatic CYP2E1. The active metabolite undergoes rearrangement to chloroacetaldehyde or is … WebEnvironmental Health Perspectives Vol. 17, pp. 217-219, 1976 Studiesonthe Metabolism of Vinyl Chloride byH. Antweiler* Vinyl chloride (VCM) is not carcinogenic by itself. it is …
WebWhen grown on ethane, EA1 cometabolizes vinyl chloride (VC) at a maximum rate of 0.350 micromol/mg volatile suspended solids/d and with a half saturation constant of 0.62 … WebChloroethylene mixtures Pharmacokinetic modeling and/n vitro metabolism of vinyl chloride, trichloroethylene, and tranv-l,2-dichloroethylene in rats. Toxicol Appl …
Web1 okt. 1976 · Vinyl chloride (VCM) is not carcinogenic by itself, it is bioactivated to the highly reactive alkylating oxirane chloroethylene oxide. Further metabolism, apparently, … Web3 jul. 2003 · Vinyl chloride was found in at least 496 of the 1,430 National Priorities ... strictly anaerobic bacterium that destroys dichloroethenes and vinyl chloride as part of …
Web1 jan. 2007 · PDF On Jan 1, 2007, Fazlul Huq published Metabolism of vinyl chloride – a molecular modeling analysis Find, read and cite all the research you need on …
Web1 mrt. 2024 · Vinyl chloride is a colorless gas with a sweet odor, which is often handled in liquid form. This toxic chemical enters water supplies as a result of industrial emissions, agricultural runoff, other means of air pollution, chemical leaks and spills, and from some household cleaning products. shoprite shares priceWebA superoxide (O2) generating system comprised of phenazine methosulfate and NADH also converts 14 C-vinyl chloride to metabolites which irreversibly bind to … shoprite share price moneywebWebVinyl chloride is mainly metabolised in the liver into reactive metabolites Vinyl chloride is mainly excreted in the urine as thiodiglycolic acid Health effects of acute exposure Acute … shoprite share priceWeb18 feb. 2024 · Vinyl chloride is a known human carcinogen associated with highly specific types of cancer like hepatic angiosarcoma (a rare type of liver cancer) and liver problems … shoprite share price todayWebvinyl chloride were used in preliminary experiments with TA 1535. A water solution of vinyl chloride was prepared by bubbling vinyl chloride gas through water in a test tube for a … shoprite share price forecastWeb1 jun. 2004 · It is demonstrated that metabolic vinyl chloride (VC) degradation by an enrichment culture originating from groundwater was not affected by an equimolar concentration (50 μM) of cis-1,2-dichloroethene (cDCE) or cis- 1,1-DCE (tDCE), and only cDCE and tDCE were cometabolically degraded in small amounts. 4 shoprite shares to buyWebVinyl chloride can exist as liquid under pressure or at low temperatures. It burns easily and is unstable at high temperatures. Vinyl chloride is only slightly soluble in water, but it is … shoprite shares south africa